Budget impact analysis of surfactant therapy for bronchiolitis in critically ill infants: the Colombian National Health System perspective

Abstract Background Severe bronchiolitis requiring mechanical ventilation was associated with an absence of surfactant activity and phosphatidylglycerol, causing airway obstruction in acute bronchiolitis. Exogen mechanically ventilated infants decreased duration stay the intensive care unit had favorable effects on oxygenation carbon dioxide removal. This study aimed to evaluate budget impact therapy for critically ill Colombia. Methods Budget analysis performed estimate economic (ST) treatment a diagnosis bronchiolitis, ventilation. The considered 4-year time horizon Colombian National Health System perspective. model estimated drug costs current scenario using humidified oxygen or adrenaline nebulization, new adding exogen surfactant. size target population calculated epidemiological national data. Univariate one-way sensitivity analyses were performed. Results In base-case ST no-ST be US$ 55,188,132 55,972,082 respectively, indicating savings equal 783,950 if is adopted routine management patients analysis, only increases cost length pediatric reduce potential ST. Conclusion cost-saving emergency settings treating severe shift approach proved economically context.